| Orangeburg to LaGrange (Georgia) | 243.12 mi (391.26 km) |
| Orangeburg to Laguna Beach (California) | 2,113.72 mi (3,401.70 km) |
| Orangeburg to Laguna Hills (California) | 2,109.62 mi (3,395.11 km) |
| Orangeburg to Laguna Niguel (California) | 2,110.75 mi (3,396.93 km) |
| Orangeburg to Laguna Woods (California) | 2,111.14 mi (3,397.56 km) |
| Orangeburg to Lahaina (Hawaii) | 4,641.30 mi (7,469.45 km) |
| Orangeburg to Lake Arbor (Maryland) | 436.66 mi (702.73 km) |
| Orangeburg to Lake Barcroft (Virginia) | 424.02 mi (682.40 km) |
| Orangeburg to Lake Butler (Florida) | 348.25 mi (560.45 km) |
| Orangeburg to Lake Charles (Louisiana) | 758.78 mi (1,221.13 km) |
| Orangeburg to Lake City (Florida) | 250.96 mi (403.88 km) |
| Orangeburg to Lake Elmo (Minnesota) | 1,020.55 mi (1,642.41 km) |
| Orangeburg to Lake Elsinore (California) | 2,087.84 mi (3,360.06 km) |
| Orangeburg to Lake Forest (California) | 2,107.21 mi (3,391.23 km) |
| Orangeburg to Lake Forest (Illinois) | 713.94 mi (1,148.98 km) |
