| Orangeburg to Eugene (Oregon) | 2,361.05 mi (3,799.75 km) |
| Orangeburg to Euless (Texas) | 937.74 mi (1,509.15 km) |
| Orangeburg to Eureka (California) | 2,411.71 mi (3,881.28 km) |
| Orangeburg to Eureka (Missouri) | 646.51 mi (1,040.45 km) |
| Orangeburg to Eustis (Florida) | 323.91 mi (521.28 km) |
| Orangeburg to Evans (Colorado) | 1,396.11 mi (2,246.82 km) |
| Orangeburg to Evans (Georgia) | 73.19 mi (117.79 km) |
| Orangeburg to Evanston (Illinois) | 698.23 mi (1,123.70 km) |
| Orangeburg to Evanston (Wyoming) | 1,727.39 mi (2,779.97 km) |
| Orangeburg to Evansville (Indiana) | 485.83 mi (781.86 km) |
| Orangeburg to Everett (Massachusetts) | 814.39 mi (1,310.63 km) |
| Orangeburg to Everett (Washington) | 2,346.63 mi (3,776.54 km) |
| Orangeburg to Evergreen Park (Illinois) | 680.03 mi (1,094.40 km) |
| Orangeburg to Ewa Beach (Hawaii) | 4,702.96 mi (7,568.68 km) |
| Orangeburg to Ewa Gentry (Hawaii) | 4,703.48 mi (7,569.52 km) |
