| Orangeburg to Clarksdale (Mississippi) | 558.66 mi (899.08 km) |
| Orangeburg to Clarkston (Georgia) | 195.25 mi (314.22 km) |
| Orangeburg to Clarksville (Indiana) | 431.75 mi (694.83 km) |
| Orangeburg to Clarksville (Tennessee) | 423.34 mi (681.31 km) |
| Orangeburg to Clawson (Michigan) | 637.04 mi (1,025.22 km) |
| Orangeburg to Clay (Alabama) | 330.72 mi (532.24 km) |
| Orangeburg to Clayton (California) | 2,305.28 mi (3,709.99 km) |
| Orangeburg to Clayton (Missouri) | 636.64 mi (1,024.57 km) |
| Orangeburg to Clayton (North Carolina) | 203.24 mi (327.08 km) |
| Orangeburg to Clayton (Ohio) | 480.39 mi (773.12 km) |
| Orangeburg to Clearfield (Utah) | 1,780.53 mi (2,865.48 km) |
| Orangeburg to Clearlake (California) | 2,337.69 mi (3,762.15 km) |
| Orangeburg to Clearwater (Florida) | 397.22 mi (639.26 km) |
| Orangeburg to Cleburne (Texas) | 961.90 mi (1,548.02 km) |
| Orangeburg to Clemmons (North Carolina) | 177.55 mi (285.73 km) |
