| Opovo to Southern Pines (North Carolina) | 4,973.59 mi (8,004.23 km) |
| Opovo to Southfield (Michigan) | 4,783.37 mi (7,698.09 km) |
| Opovo to Southgate (Michigan) | 4,794.07 mi (7,715.32 km) |
| Opovo to Southlake (Texas) | 5,779.93 mi (9,301.90 km) |
| Opovo to Spanaway (Washington) | 5,681.95 mi (9,144.22 km) |
| Opovo to Spanish Fork (Utah) | 5,845.97 mi (9,408.18 km) |
| Opovo to Spanish Lake (Missouri) | 5,221.06 mi (8,402.48 km) |
| Opovo to Spanish Springs (Nevada) | 6,082.11 mi (9,788.21 km) |
| Opovo to Sparks (Nevada) | 6,088.36 mi (9,798.27 km) |
| Opovo to Spartanburg (South Carolina) | 5,088.86 mi (8,189.73 km) |
| Opovo to Spearfish (South Dakota) | 5,371.18 mi (8,644.07 km) |
| Opovo to Speedway (Indiana) | 5,023.86 mi (8,085.12 km) |
| Opovo to Spencer (Iowa) | 5,171.31 mi (8,322.43 km) |
| Opovo to Spokane (Washington) | 5,540.52 mi (8,916.60 km) |
| Opovo to Spokane Valley (Washington) | 5,536.34 mi (8,909.88 km) |
