| Opelousas to Yonkers (New York) | 1,245.64 mi (2,004.67 km) |
| Opelousas to Yorba Linda (California) | 1,515.70 mi (2,439.28 km) |
| Opelousas to York (Pennsylvania) | 1,081.63 mi (1,740.71 km) |
| Opelousas to Yorktown (Indiana) | 762.53 mi (1,227.17 km) |
| Opelousas to Yorkville (Illinois) | 795.14 mi (1,279.65 km) |
| Opelousas to Youngstown (Ohio) | 969.97 mi (1,561.02 km) |
| Opelousas to Youngsville (Louisiana) | 30.06 mi (48.38 km) |
| Opelousas to Ypsilanti (Michigan) | 935.36 mi (1,505.32 km) |
| Opelousas to Yuba City (California) | 1,769.26 mi (2,847.35 km) |
| Opelousas to Yucaipa (California) | 1,474.35 mi (2,372.74 km) |
| Opelousas to Yucca Valley (California) | 1,439.15 mi (2,316.09 km) |
| Opelousas to Yukon (Oklahoma) | 476.74 mi (767.24 km) |
| Opelousas to Yulee (Florida) | 625.22 mi (1,006.19 km) |
| Opelousas to Yuma (Arizona) | 1,327.97 mi (2,137.16 km) |
| Opelousas to Zachary (Louisiana) | 55.45 mi (89.24 km) |
