| Opelousas to Worthington (Ohio) | 834.55 mi (1,343.08 km) |
| Opelousas to Wright (Florida) | 323.91 mi (521.28 km) |
| Opelousas to Wyandanch (New York) | 1,262.15 mi (2,031.24 km) |
| Opelousas to Wyandotte (Michigan) | 946.64 mi (1,523.46 km) |
| Opelousas to Wylie (Texas) | 312.90 mi (503.56 km) |
| Opelousas to Wyndham (Virginia) | 962.87 mi (1,549.60 km) |
| Opelousas to Wyoming (Michigan) | 923.75 mi (1,486.64 km) |
| Opelousas to Wyomissing (Pennsylvania) | 1,129.14 mi (1,817.18 km) |
| Opelousas to Xenia (Ohio) | 781.56 mi (1,257.81 km) |
| Opelousas to Yakima (Washington) | 1,879.81 mi (3,025.26 km) |
| Opelousas to Yankton (South Dakota) | 903.06 mi (1,453.33 km) |
| Opelousas to Yauco (Puerto Rico) | 1,801.30 mi (2,898.91 km) |
| Opelousas to Yazoo City (Mississippi) | 189.08 mi (304.29 km) |
| Opelousas to Yeadon (Pennsylvania) | 1,147.77 mi (1,847.16 km) |
| Opelousas to Yelm (Washington) | 1,979.00 mi (3,184.89 km) |
