| Opelousas to Wayne (Michigan) | 943.81 mi (1,518.92 km) |
| Opelousas to Waynesboro (Pennsylvania) | 1,035.76 mi (1,666.90 km) |
| Opelousas to Waynesboro (Virginia) | 913.68 mi (1,470.42 km) |
| Opelousas to Weatherford (Oklahoma) | 515.77 mi (830.06 km) |
| Opelousas to Weatherford (Texas) | 368.38 mi (592.86 km) |
| Opelousas to Webb City (Missouri) | 477.14 mi (767.88 km) |
| Opelousas to Webster (Texas) | 194.21 mi (312.55 km) |
| Opelousas to Webster Groves (Missouri) | 565.56 mi (910.18 km) |
| Opelousas to Weddington (North Carolina) | 727.95 mi (1,171.52 km) |
| Opelousas to Weigelstown (Pennsylvania) | 1,077.94 mi (1,734.78 km) |
| Opelousas to Weirton (West Virginia) | 939.59 mi (1,512.12 km) |
| Opelousas to Wekiwa Springs (Florida) | 652.18 mi (1,049.58 km) |
| Opelousas to Welby (Colorado) | 969.50 mi (1,560.27 km) |
| Opelousas to Wellington (Colorado) | 1,008.43 mi (1,622.91 km) |
| Opelousas to Wellington (Florida) | 764.59 mi (1,230.49 km) |
