| Opelousas to Stephenville (Texas) | 380.43 mi (612.25 km) |
| Opelousas to Sterling (Colorado) | 934.59 mi (1,504.07 km) |
| Opelousas to Sterling (Illinois) | 790.18 mi (1,271.67 km) |
| Opelousas to Sterling (Virginia) | 1,016.32 mi (1,635.61 km) |
| Opelousas to Sterling Heights (Michigan) | 971.36 mi (1,563.26 km) |
| Opelousas to Steubenville (Ohio) | 934.41 mi (1,503.79 km) |
| Opelousas to Stevens Point (Wisconsin) | 976.99 mi (1,572.31 km) |
| Opelousas to Stevenson Ranch (California) | 1,563.63 mi (2,516.42 km) |
| Opelousas to Stillwater (Minnesota) | 1,004.89 mi (1,617.22 km) |
| Opelousas to Stillwater (Oklahoma) | 482.66 mi (776.77 km) |
| Opelousas to Stockbridge (Georgia) | 504.32 mi (811.62 km) |
| Opelousas to Stockton (California) | 1,738.63 mi (2,798.05 km) |
| Opelousas to Stone Ridge (Virginia) | 1,006.69 mi (1,620.10 km) |
| Opelousas to Stonecrest (Georgia) | 513.43 mi (826.29 km) |
| Opelousas to Stony Brook (New York) | 1,278.11 mi (2,056.92 km) |
