| Opelousas to St. George (Utah) | 1,310.83 mi (2,109.58 km) |
| Opelousas to St. Helens (Oregon) | 1,958.11 mi (3,151.27 km) |
| Opelousas to St. James (New York) | 1,276.01 mi (2,053.55 km) |
| Opelousas to St. John (Indiana) | 796.86 mi (1,282.42 km) |
| Opelousas to St. Joseph (Missouri) | 656.45 mi (1,056.46 km) |
| Opelousas to St. Louis (Missouri) | 570.01 mi (917.34 km) |
| Opelousas to St. Louis Park (Minnesota) | 999.00 mi (1,607.74 km) |
| Opelousas to St. Marys (Georgia) | 624.72 mi (1,005.39 km) |
| Opelousas to St. Marys (Pennsylvania) | 1,067.09 mi (1,717.32 km) |
| Opelousas to St. Matthews (Kentucky) | 647.52 mi (1,042.08 km) |
| Opelousas to St. Michael (Minnesota) | 1,017.77 mi (1,637.94 km) |
| Opelousas to St. Paul (Minnesota) | 998.05 mi (1,606.20 km) |
| Opelousas to St. Peter (Minnesota) | 959.30 mi (1,543.84 km) |
| Opelousas to St. Peters (Missouri) | 576.63 mi (927.99 km) |
| Opelousas to St. Petersburg (Florida) | 598.45 mi (963.12 km) |
