| Opelousas to Somersworth (New Hampshire) | 1,457.55 mi (2,345.69 km) |
| Opelousas to Somerton (Arizona) | 1,336.72 mi (2,151.24 km) |
| Opelousas to Somerville (Massachusetts) | 1,418.87 mi (2,283.44 km) |
| Opelousas to Somerville (New Jersey) | 1,199.01 mi (1,929.62 km) |
| Opelousas to Sonoma (California) | 1,803.53 mi (2,902.50 km) |
| Opelousas to Soquel (California) | 1,764.92 mi (2,840.37 km) |
| Opelousas to South Bend (Indiana) | 835.49 mi (1,344.59 km) |
| Opelousas to South Bradenton (Florida) | 611.61 mi (984.29 km) |
| Opelousas to South Burlington (Vermont) | 1,406.47 mi (2,263.50 km) |
| Opelousas to South Charleston (West Virginia) | 799.43 mi (1,286.56 km) |
| Opelousas to South Daytona (Florida) | 670.11 mi (1,078.44 km) |
| Opelousas to South El Monte (California) | 1,531.91 mi (2,465.38 km) |
| Opelousas to South Elgin (Illinois) | 819.29 mi (1,318.52 km) |
| Opelousas to South Euclid (Ohio) | 960.43 mi (1,545.66 km) |
| Opelousas to South Farmingdale (New York) | 1,257.23 mi (2,023.32 km) |
