| Opelousas to Shoreview (Minnesota) | 1,007.55 mi (1,621.49 km) |
| Opelousas to Shorewood (Illinois) | 789.36 mi (1,270.35 km) |
| Opelousas to Shorewood (Wisconsin) | 898.39 mi (1,445.81 km) |
| Opelousas to Short Hills (New Jersey) | 1,217.62 mi (1,959.58 km) |
| Opelousas to Short Pump (Virginia) | 961.33 mi (1,547.12 km) |
| Opelousas to Show Low (Arizona) | 1,077.43 mi (1,733.95 km) |
| Opelousas to Shreveport (Louisiana) | 167.82 mi (270.07 km) |
| Opelousas to Sicklerville (New Jersey) | 1,153.61 mi (1,856.55 km) |
| Opelousas to Sidney (Ohio) | 807.75 mi (1,299.95 km) |
| Opelousas to Sierra Madre (California) | 1,532.33 mi (2,466.05 km) |
| Opelousas to Sierra Vista (Arizona) | 1,080.51 mi (1,738.92 km) |
| Opelousas to Sierra Vista Southeast (Arizona) | 1,074.82 mi (1,729.75 km) |
| Opelousas to Signal Hill (California) | 1,538.30 mi (2,475.65 km) |
| Opelousas to Sikeston (Missouri) | 462.18 mi (743.81 km) |
| Opelousas to Siloam Springs (Arkansas) | 415.74 mi (669.08 km) |
