| Opelousas to Shelton (Connecticut) | 1,290.89 mi (2,077.48 km) |
| Opelousas to Shelton (Washington) | 2,007.72 mi (3,231.11 km) |
| Opelousas to Shenandoah (Louisiana) | 64.86 mi (104.38 km) |
| Opelousas to Shepherdsville (Kentucky) | 630.63 mi (1,014.91 km) |
| Opelousas to Sheridan (Wyoming) | 1,274.33 mi (2,050.84 km) |
| Opelousas to Sherman (Texas) | 341.40 mi (549.43 km) |
| Opelousas to Sherrelwood (Colorado) | 970.96 mi (1,562.61 km) |
| Opelousas to Sherwood (Arkansas) | 298.95 mi (481.11 km) |
| Opelousas to Sherwood (Oregon) | 1,946.67 mi (3,132.87 km) |
| Opelousas to Shiloh (Illinois) | 568.17 mi (914.38 km) |
| Opelousas to Shiloh (Ohio) | 779.40 mi (1,254.32 km) |
| Opelousas to Shiloh (Pennsylvania) | 1,079.22 mi (1,736.84 km) |
| Opelousas to Shirley (New York) | 1,286.19 mi (2,069.92 km) |
| Opelousas to Shively (Kentucky) | 638.97 mi (1,028.32 km) |
| Opelousas to Shoreline (Washington) | 1,990.71 mi (3,203.73 km) |
