| Opelousas to San Luis Obispo (California) | 1,684.42 mi (2,710.82 km) |
| Opelousas to San Marcos (California) | 1,480.44 mi (2,382.54 km) |
| Opelousas to San Marcos (Texas) | 352.42 mi (567.17 km) |
| Opelousas to San Marino (California) | 1,535.80 mi (2,471.63 km) |
| Opelousas to San Mateo (California) | 1,788.99 mi (2,879.10 km) |
| Opelousas to San Pablo (California) | 1,794.15 mi (2,887.41 km) |
| Opelousas to San Rafael (California) | 1,804.09 mi (2,903.41 km) |
| Opelousas to San Ramon (California) | 1,770.39 mi (2,849.16 km) |
| Opelousas to San Tan Valley (Arizona) | 1,156.20 mi (1,860.72 km) |
| Opelousas to Sand Springs (Oklahoma) | 452.46 mi (728.16 km) |
| Opelousas to Sandusky (Ohio) | 917.62 mi (1,476.77 km) |
| Opelousas to Sandy (Oregon) | 1,921.79 mi (3,092.82 km) |
| Opelousas to Sandy (Utah) | 1,305.62 mi (2,101.19 km) |
| Opelousas to Sandy Springs (Georgia) | 508.40 mi (818.18 km) |
| Opelousas to Sanford (Florida) | 659.53 mi (1,061.40 km) |
