| Opelousas to Saddlebrooke (Arizona) | 1,114.00 mi (1,792.80 km) |
| Opelousas to Safety Harbor (Florida) | 591.59 mi (952.07 km) |
| Opelousas to Saginaw (Michigan) | 996.40 mi (1,603.56 km) |
| Opelousas to Saginaw (Texas) | 350.13 mi (563.48 km) |
| Opelousas to Sahuarita (Arizona) | 1,118.50 mi (1,800.05 km) |
| Opelousas to Saks (Alabama) | 425.67 mi (685.04 km) |
| Opelousas to Salem (Massachusetts) | 1,431.82 mi (2,304.29 km) |
| Opelousas to Salem (Ohio) | 952.98 mi (1,533.68 km) |
| Opelousas to Salem (Oregon) | 1,944.37 mi (3,129.16 km) |
| Opelousas to Salem (Virginia) | 831.85 mi (1,338.73 km) |
| Opelousas to Salem Lakes (Wisconsin) | 858.13 mi (1,381.03 km) |
| Opelousas to Salida (California) | 1,723.74 mi (2,774.08 km) |
| Opelousas to Salina (Kansas) | 652.96 mi (1,050.84 km) |
| Opelousas to Salinas (California) | 1,745.40 mi (2,808.95 km) |
| Opelousas to Salisbury (Maryland) | 1,082.66 mi (1,742.38 km) |
