| Opelousas to Reidsville (North Carolina) | 819.53 mi (1,318.91 km) |
| Opelousas to Reisterstown (Maryland) | 1,059.41 mi (1,704.96 km) |
| Opelousas to Rendon (Texas) | 334.90 mi (538.98 km) |
| Opelousas to Reno (Nevada) | 1,681.51 mi (2,706.12 km) |
| Opelousas to Renton (Washington) | 1,976.07 mi (3,180.18 km) |
| Opelousas to Republic (Missouri) | 464.02 mi (746.77 km) |
| Opelousas to Reston (Virginia) | 1,017.09 mi (1,636.85 km) |
| Opelousas to Revere (Massachusetts) | 1,424.16 mi (2,291.96 km) |
| Opelousas to Rexburg (Idaho) | 1,415.24 mi (2,277.61 km) |
| Opelousas to Reynoldsburg (Ohio) | 835.31 mi (1,344.31 km) |
| Opelousas to Rialto (California) | 1,494.41 mi (2,405.01 km) |
| Opelousas to Richardson (Texas) | 320.10 mi (515.15 km) |
| Opelousas to Richfield (Minnesota) | 993.71 mi (1,599.21 km) |
| Opelousas to Richfield (Wisconsin) | 903.31 mi (1,453.74 km) |
| Opelousas to Richland (Washington) | 1,816.77 mi (2,923.80 km) |
