| Opelousas to Orangevale (California) | 1,741.67 mi (2,802.95 km) |
| Opelousas to Orchards (Washington) | 1,940.99 mi (3,123.71 km) |
| Opelousas to Orcutt (California) | 1,669.19 mi (2,686.30 km) |
| Opelousas to Oregon (Ohio) | 906.78 mi (1,459.32 km) |
| Opelousas to Oregon (Wisconsin) | 869.51 mi (1,399.34 km) |
| Opelousas to Oregon City (Oregon) | 1,934.90 mi (3,113.92 km) |
| Opelousas to Orem (Utah) | 1,290.29 mi (2,076.52 km) |
| Opelousas to Orinda (California) | 1,784.57 mi (2,871.99 km) |
| Opelousas to Orland Park (Illinois) | 800.87 mi (1,288.88 km) |
| Opelousas to Orlando (Florida) | 661.15 mi (1,064.01 km) |
| Opelousas to Ormond Beach (Florida) | 662.77 mi (1,066.62 km) |
| Opelousas to Oro Valley (Arizona) | 1,119.66 mi (1,801.91 km) |
| Opelousas to Oroville (California) | 1,770.10 mi (2,848.71 km) |
| Opelousas to Oshkosh (Wisconsin) | 952.20 mi (1,532.42 km) |
| Opelousas to Oskaloosa (Iowa) | 744.58 mi (1,198.29 km) |
