| Opelousas to Odenton (Maryland) | 1,051.46 mi (1,692.15 km) |
| Opelousas to Odessa (Texas) | 613.47 mi (987.29 km) |
| Opelousas to Ogden (Utah) | 1,331.47 mi (2,142.79 km) |
| Opelousas to Oildale (California) | 1,593.04 mi (2,563.75 km) |
| Opelousas to Ojus (Florida) | 790.71 mi (1,272.53 km) |
| Opelousas to Okemos (Michigan) | 941.92 mi (1,515.87 km) |
| Opelousas to Oklahoma City (Oklahoma) | 464.26 mi (747.15 km) |
| Opelousas to Okmulgee (Oklahoma) | 418.53 mi (673.55 km) |
| Opelousas to Olathe (Kansas) | 597.98 mi (962.36 km) |
| Opelousas to Old Jamestown (Missouri) | 583.42 mi (938.92 km) |
| Opelousas to Oldsmar (Florida) | 592.15 mi (952.97 km) |
| Opelousas to Olean (New York) | 1,099.60 mi (1,769.64 km) |
| Opelousas to Olive Branch (Mississippi) | 332.83 mi (535.65 km) |
| Opelousas to Olivehurst (California) | 1,764.25 mi (2,839.28 km) |
| Opelousas to Olney (Maryland) | 1,036.69 mi (1,668.39 km) |
