| Opelousas to Montgomeryville (Pennsylvania) | 1,159.21 mi (1,865.57 km) |
| Opelousas to Monticello (Minnesota) | 1,025.00 mi (1,649.57 km) |
| Opelousas to Montrose (Colorado) | 1,050.54 mi (1,690.68 km) |
| Opelousas to Moody (Alabama) | 389.84 mi (627.38 km) |
| Opelousas to Moore (Oklahoma) | 455.95 mi (733.78 km) |
| Opelousas to Moorestown-Lenola (New Jersey) | 1,162.24 mi (1,870.45 km) |
| Opelousas to Mooresville (North Carolina) | 738.91 mi (1,189.16 km) |
| Opelousas to Moorhead (Minnesota) | 1,156.26 mi (1,860.81 km) |
| Opelousas to Moorpark (California) | 1,579.81 mi (2,542.45 km) |
| Opelousas to Moraga (California) | 1,781.18 mi (2,866.54 km) |
| Opelousas to Moreno Valley (California) | 1,483.29 mi (2,387.12 km) |
| Opelousas to Morgan City (Louisiana) | 77.75 mi (125.13 km) |
| Opelousas to Morgan Hill (California) | 1,749.11 mi (2,814.93 km) |
| Opelousas to Morganton (North Carolina) | 699.85 mi (1,126.30 km) |
| Opelousas to Morgantown (West Virginia) | 929.63 mi (1,496.09 km) |
