| Opelousas to Medford (Massachusetts) | 1,419.61 mi (2,284.65 km) |
| Opelousas to Medford (New York) | 1,281.94 mi (2,063.09 km) |
| Opelousas to Medford (Oregon) | 1,881.43 mi (3,027.87 km) |
| Opelousas to Medina (Ohio) | 928.45 mi (1,494.19 km) |
| Opelousas to Medulla (Florida) | 633.68 mi (1,019.81 km) |
| Opelousas to Mehlville (Missouri) | 560.20 mi (901.55 km) |
| Opelousas to Melbourne (Florida) | 707.53 mi (1,138.66 km) |
| Opelousas to Melissa (Texas) | 324.57 mi (522.34 km) |
| Opelousas to Melrose (Massachusetts) | 1,422.90 mi (2,289.94 km) |
| Opelousas to Melrose Park (Illinois) | 820.25 mi (1,320.06 km) |
| Opelousas to Melville (New York) | 1,261.13 mi (2,029.59 km) |
| Opelousas to Melvindale (Michigan) | 949.93 mi (1,528.76 km) |
| Opelousas to Memphis (Florida) | 610.67 mi (982.78 km) |
| Opelousas to Memphis (Tennessee) | 339.65 mi (546.61 km) |
| Opelousas to Menasha (Wisconsin) | 966.48 mi (1,555.40 km) |
