| Opelousas to McHenry (Illinois) | 842.71 mi (1,356.22 km) |
| Opelousas to McKeesport (Pennsylvania) | 964.95 mi (1,552.94 km) |
| Opelousas to McKinleyville (California) | 1,920.55 mi (3,090.82 km) |
| Opelousas to McKinney (Texas) | 326.44 mi (525.35 km) |
| Opelousas to McLean (Virginia) | 1,023.93 mi (1,647.85 km) |
| Opelousas to McMinnville (Oregon) | 1,958.91 mi (3,152.56 km) |
| Opelousas to McMinnville (Tennessee) | 509.79 mi (820.43 km) |
| Opelousas to McNair (Virginia) | 1,014.12 mi (1,632.07 km) |
| Opelousas to McPherson (Kansas) | 628.11 mi (1,010.85 km) |
| Opelousas to Mead Valley (California) | 1,487.69 mi (2,394.21 km) |
| Opelousas to Meadow Woods (Florida) | 662.54 mi (1,066.25 km) |
| Opelousas to Meadowbrook (Virginia) | 961.72 mi (1,547.74 km) |
| Opelousas to Meadville (Pennsylvania) | 1,015.12 mi (1,633.68 km) |
| Opelousas to Mebane (North Carolina) | 832.41 mi (1,339.64 km) |
| Opelousas to Mechanicsville (Virginia) | 973.42 mi (1,566.56 km) |
