| Opelousas to Lovington (New Mexico) | 680.86 mi (1,095.73 km) |
| Opelousas to Lowell (Indiana) | 787.98 mi (1,268.14 km) |
| Opelousas to Lowell (Massachusetts) | 1,417.33 mi (2,280.98 km) |
| Opelousas to Lower Burrell (Pennsylvania) | 980.99 mi (1,578.75 km) |
| Opelousas to Lowes Island (Virginia) | 1,020.23 mi (1,641.90 km) |
| Opelousas to Lubbock (Texas) | 611.20 mi (983.64 km) |
| Opelousas to Lufkin (Texas) | 166.21 mi (267.49 km) |
| Opelousas to Luling (Louisiana) | 111.90 mi (180.09 km) |
| Opelousas to Lumberton (North Carolina) | 810.95 mi (1,305.10 km) |
| Opelousas to Lumberton (Texas) | 128.03 mi (206.04 km) |
| Opelousas to Lutz (Florida) | 603.07 mi (970.55 km) |
| Opelousas to Lynbrook (New York) | 1,244.81 mi (2,003.33 km) |
| Opelousas to Lynchburg (Virginia) | 876.97 mi (1,411.35 km) |
| Opelousas to Lynden (Washington) | 2,032.28 mi (3,270.64 km) |
| Opelousas to Lyndhurst (Ohio) | 961.17 mi (1,546.86 km) |
