| Opelousas to Isabela (Puerto Rico) | 1,774.97 mi (2,856.54 km) |
| Opelousas to Iselin (New Jersey) | 1,212.34 mi (1,951.07 km) |
| Opelousas to Isla Vista (California) | 1,636.22 mi (2,633.25 km) |
| Opelousas to Issaquah (Washington) | 1,971.94 mi (3,173.53 km) |
| Opelousas to Ithaca (New York) | 1,190.94 mi (1,916.63 km) |
| Opelousas to Ives Estates (Florida) | 789.26 mi (1,270.18 km) |
| Opelousas to Jackson (Michigan) | 914.39 mi (1,471.57 km) |
| Opelousas to Jackson (Mississippi) | 165.67 mi (266.62 km) |
| Opelousas to Jackson (Missouri) | 493.55 mi (794.30 km) |
| Opelousas to Jackson (Tennessee) | 401.02 mi (645.39 km) |
| Opelousas to Jackson (Wyoming) | 1,359.59 mi (2,188.05 km) |
| Opelousas to Jacksonville (Alabama) | 433.93 mi (698.34 km) |
| Opelousas to Jacksonville (Arkansas) | 300.95 mi (484.33 km) |
| Opelousas to Jacksonville (Florida) | 619.92 mi (997.66 km) |
| Opelousas to Jacksonville (Illinois) | 644.42 mi (1,037.10 km) |
