| Opelousas to Indianapolis (Indiana) | 721.41 mi (1,161.00 km) |
| Opelousas to Indianola (Iowa) | 753.36 mi (1,212.42 km) |
| Opelousas to Indio (California) | 1,427.15 mi (2,296.78 km) |
| Opelousas to Inglewood (California) | 1,548.67 mi (2,492.34 km) |
| Opelousas to Inkster (Michigan) | 946.80 mi (1,523.72 km) |
| Opelousas to Inver Grove Heights (Minnesota) | 989.43 mi (1,592.33 km) |
| Opelousas to Inwood (New York) | 1,240.10 mi (1,995.76 km) |
| Opelousas to Iona (Florida) | 673.63 mi (1,084.11 km) |
| Opelousas to Ionia (Michigan) | 942.93 mi (1,517.50 km) |
| Opelousas to Iowa City (Iowa) | 769.67 mi (1,238.66 km) |
| Opelousas to Irmo (South Carolina) | 681.55 mi (1,096.84 km) |
| Opelousas to Irondale (Alabama) | 379.80 mi (611.23 km) |
| Opelousas to Ironton (Ohio) | 768.93 mi (1,237.48 km) |
| Opelousas to Irvine (California) | 1,515.46 mi (2,438.90 km) |
| Opelousas to Irving (Texas) | 329.47 mi (530.23 km) |
