| Opelousas to Friendly (Maryland) | 1,028.45 mi (1,655.12 km) |
| Opelousas to Friendswood (Texas) | 199.17 mi (320.53 km) |
| Opelousas to Frisco (Texas) | 332.27 mi (534.74 km) |
| Opelousas to Front Royal (Virginia) | 977.78 mi (1,573.58 km) |
| Opelousas to Fruit Cove (Florida) | 624.64 mi (1,005.26 km) |
| Opelousas to Fruita (Colorado) | 1,113.87 mi (1,792.59 km) |
| Opelousas to Fruitville (Florida) | 621.87 mi (1,000.80 km) |
| Opelousas to Fuller Heights (Florida) | 633.80 mi (1,020.00 km) |
| Opelousas to Fullerton (California) | 1,524.66 mi (2,453.70 km) |
| Opelousas to Fullerton (Pennsylvania) | 1,161.78 mi (1,869.71 km) |
| Opelousas to Fulshear (Texas) | 234.21 mi (376.92 km) |
| Opelousas to Fulton (Missouri) | 575.59 mi (926.32 km) |
| Opelousas to Fulton (New York) | 1,232.80 mi (1,984.00 km) |
| Opelousas to Fuquay-Varina (North Carolina) | 845.30 mi (1,360.38 km) |
| Opelousas to Gadsden (Alabama) | 428.25 mi (689.21 km) |
