| Opelousas to Eugene (Oregon) | 1,928.92 mi (3,104.29 km) |
| Opelousas to Euless (Texas) | 334.87 mi (538.92 km) |
| Opelousas to Eureka (California) | 1,922.02 mi (3,093.19 km) |
| Opelousas to Eureka (Missouri) | 557.01 mi (896.42 km) |
| Opelousas to Eustis (Florida) | 634.81 mi (1,021.62 km) |
| Opelousas to Evans (Colorado) | 982.88 mi (1,581.80 km) |
| Opelousas to Evans (Georgia) | 618.83 mi (995.91 km) |
| Opelousas to Evanston (Illinois) | 832.37 mi (1,339.57 km) |
| Opelousas to Evanston (Wyoming) | 1,286.61 mi (2,070.60 km) |
| Opelousas to Evansville (Indiana) | 577.13 mi (928.81 km) |
| Opelousas to Everett (Massachusetts) | 1,421.48 mi (2,287.66 km) |
| Opelousas to Everett (Washington) | 1,989.33 mi (3,201.52 km) |
| Opelousas to Evergreen Park (Illinois) | 810.97 mi (1,305.13 km) |
| Opelousas to Ewa Beach (Hawaii) | 4,090.55 mi (6,583.11 km) |
| Opelousas to Ewa Gentry (Hawaii) | 4,091.21 mi (6,584.17 km) |
