| Opelousas to El Segundo (California) | 1,551.89 mi (2,497.52 km) |
| Opelousas to El Sobrante (California) | 1,497.95 mi (2,410.71 km) |
| Opelousas to Eldersburg (Maryland) | 1,051.25 mi (1,691.82 km) |
| Opelousas to Elfers (Florida) | 585.48 mi (942.24 km) |
| Opelousas to Elgin (Illinois) | 822.31 mi (1,323.38 km) |
| Opelousas to Elizabeth (New Jersey) | 1,221.35 mi (1,965.57 km) |
| Opelousas to Elizabeth City (North Carolina) | 995.42 mi (1,601.97 km) |
| Opelousas to Elizabethton (Tennessee) | 694.68 mi (1,117.99 km) |
| Opelousas to Elizabethtown (Kentucky) | 609.50 mi (980.90 km) |
| Opelousas to Elizabethtown (Pennsylvania) | 1,094.52 mi (1,761.46 km) |
| Opelousas to Elk City (Oklahoma) | 542.21 mi (872.60 km) |
| Opelousas to Elk Grove (California) | 1,747.23 mi (2,811.89 km) |
| Opelousas to Elk Grove Village (Illinois) | 825.06 mi (1,327.80 km) |
| Opelousas to Elk Plain (Washington) | 1,970.75 mi (3,171.62 km) |
| Opelousas to Elk River (Minnesota) | 1,026.16 mi (1,651.44 km) |
