| Opelousas to Duluth (Minnesota) | 1,122.80 mi (1,806.97 km) |
| Opelousas to Dumas (Texas) | 679.45 mi (1,093.47 km) |
| Opelousas to Dumont (New Jersey) | 1,239.93 mi (1,995.47 km) |
| Opelousas to Duncan (Oklahoma) | 438.83 mi (706.22 km) |
| Opelousas to Duncanville (Texas) | 319.83 mi (514.72 km) |
| Opelousas to Dundalk (Maryland) | 1,067.72 mi (1,718.33 km) |
| Opelousas to Dunedin (Florida) | 585.85 mi (942.83 km) |
| Opelousas to Dunkirk (New York) | 1,085.41 mi (1,746.79 km) |
| Opelousas to Dunmore (Pennsylvania) | 1,185.82 mi (1,908.39 km) |
| Opelousas to Dunwoody (Georgia) | 511.56 mi (823.27 km) |
| Opelousas to Durango (Colorado) | 1,016.76 mi (1,636.32 km) |
| Opelousas to Durant (Oklahoma) | 347.64 mi (559.48 km) |
| Opelousas to Durham (North Carolina) | 848.60 mi (1,365.69 km) |
| Opelousas to Dyer (Indiana) | 799.71 mi (1,287.01 km) |
| Opelousas to Dyersburg (Tennessee) | 412.16 mi (663.31 km) |
