| Opelousas to Darby (Pennsylvania) | 1,147.00 mi (1,845.91 km) |
| Opelousas to Dardenne Prairie (Missouri) | 573.86 mi (923.54 km) |
| Opelousas to Darien (Illinois) | 807.97 mi (1,300.31 km) |
| Opelousas to Davenport (Iowa) | 766.60 mi (1,233.73 km) |
| Opelousas to Davidson (North Carolina) | 736.09 mi (1,184.62 km) |
| Opelousas to Davie (Florida) | 779.94 mi (1,255.19 km) |
| Opelousas to Davis (California) | 1,767.61 mi (2,844.69 km) |
| Opelousas to Dayton (Nevada) | 1,662.28 mi (2,675.18 km) |
| Opelousas to Dayton (Ohio) | 778.45 mi (1,252.80 km) |
| Opelousas to Daytona Beach (Florida) | 664.19 mi (1,068.90 km) |
| Opelousas to De Pere (Wisconsin) | 985.20 mi (1,585.53 km) |
| Opelousas to De Witt (New York) | 1,233.01 mi (1,984.34 km) |
| Opelousas to Dearborn (Michigan) | 950.79 mi (1,530.15 km) |
| Opelousas to Dearborn Heights (Michigan) | 949.19 mi (1,527.57 km) |
| Opelousas to DeBary (Florida) | 655.25 mi (1,054.53 km) |
