| Opelousas to Crawfordsville (Indiana) | 719.32 mi (1,157.63 km) |
| Opelousas to Crest Hill (Illinois) | 794.58 mi (1,278.76 km) |
| Opelousas to Crestview (Florida) | 327.48 mi (527.03 km) |
| Opelousas to Crestwood (Illinois) | 805.37 mi (1,296.12 km) |
| Opelousas to Crestwood (Missouri) | 563.31 mi (906.55 km) |
| Opelousas to Creve Coeur (Missouri) | 569.84 mi (917.07 km) |
| Opelousas to Crofton (Maryland) | 1,050.35 mi (1,690.38 km) |
| Opelousas to Crossville (Tennessee) | 553.50 mi (890.77 km) |
| Opelousas to Crowley (Louisiana) | 27.54 mi (44.32 km) |
| Opelousas to Crowley (Texas) | 341.49 mi (549.57 km) |
| Opelousas to Crown Point (Indiana) | 797.26 mi (1,283.07 km) |
| Opelousas to Crystal (Minnesota) | 1,005.11 mi (1,617.56 km) |
| Opelousas to Crystal Lake (Illinois) | 835.12 mi (1,344.00 km) |
| Opelousas to Cudahy (California) | 1,539.43 mi (2,477.48 km) |
| Opelousas to Cudahy (Wisconsin) | 889.12 mi (1,430.90 km) |
