| Opelousas to Cloverleaf (Texas) | 191.53 mi (308.25 km) |
| Opelousas to Cloverly (Maryland) | 1,038.62 mi (1,671.49 km) |
| Opelousas to Clovis (California) | 1,639.26 mi (2,638.13 km) |
| Opelousas to Clovis (New Mexico) | 701.21 mi (1,128.49 km) |
| Opelousas to Clute (Texas) | 224.22 mi (360.84 km) |
| Opelousas to Coachella (California) | 1,421.77 mi (2,288.12 km) |
| Opelousas to Coalinga (California) | 1,669.50 mi (2,686.80 km) |
| Opelousas to Coamo (Puerto Rico) | 1,827.09 mi (2,940.41 km) |
| Opelousas to Coatesville (Pennsylvania) | 1,123.53 mi (1,808.14 km) |
| Opelousas to Cockeysville (Maryland) | 1,068.77 mi (1,720.02 km) |
| Opelousas to Cocoa (Florida) | 696.28 mi (1,120.55 km) |
| Opelousas to Cocoa Beach (Florida) | 705.39 mi (1,135.21 km) |
| Opelousas to Coconut Creek (Florida) | 779.74 mi (1,254.87 km) |
| Opelousas to Coeur d'Alene (Idaho) | 1,764.50 mi (2,839.69 km) |
| Opelousas to Cohoes (New York) | 1,319.03 mi (2,122.77 km) |
