| Opelousas to Clarksdale (Mississippi) | 268.36 mi (431.88 km) |
| Opelousas to Clarkston (Georgia) | 511.53 mi (823.24 km) |
| Opelousas to Clarksville (Indiana) | 647.45 mi (1,041.97 km) |
| Opelousas to Clarksville (Tennessee) | 498.73 mi (802.62 km) |
| Opelousas to Clawson (Michigan) | 965.43 mi (1,553.71 km) |
| Opelousas to Clay (Alabama) | 387.90 mi (624.27 km) |
| Opelousas to Clayton (California) | 1,771.67 mi (2,851.23 km) |
| Opelousas to Clayton (Missouri) | 569.72 mi (916.88 km) |
| Opelousas to Clayton (North Carolina) | 864.09 mi (1,390.62 km) |
| Opelousas to Clayton (Ohio) | 779.24 mi (1,254.07 km) |
| Opelousas to Clearfield (Utah) | 1,330.09 mi (2,140.58 km) |
| Opelousas to Clearlake (California) | 1,819.74 mi (2,928.59 km) |
| Opelousas to Clearwater (Florida) | 588.46 mi (947.04 km) |
| Opelousas to Cleburne (Texas) | 338.86 mi (545.35 km) |
| Opelousas to Clemmons (North Carolina) | 774.51 mi (1,246.45 km) |
