| Old Jamestown to Storm Lake (Iowa) | 367.53 mi (591.48 km) |
| Old Jamestown to Storrs (Connecticut) | 969.89 mi (1,560.88 km) |
| Old Jamestown to Stoughton (Wisconsin) | 287.59 mi (462.84 km) |
| Old Jamestown to Stow (Ohio) | 495.16 mi (796.88 km) |
| Old Jamestown to Streamwood (Illinois) | 246.15 mi (396.13 km) |
| Old Jamestown to Streator (Illinois) | 175.67 mi (282.71 km) |
| Old Jamestown to Streetsboro (Ohio) | 500.81 mi (805.97 km) |
| Old Jamestown to Strongsville (Ohio) | 478.23 mi (769.63 km) |
| Old Jamestown to Stuart (Florida) | 991.29 mi (1,595.32 km) |
| Old Jamestown to Stuarts Draft (Virginia) | 611.12 mi (983.51 km) |
| Old Jamestown to Sturgis (Michigan) | 327.83 mi (527.60 km) |
| Old Jamestown to Suamico (Wisconsin) | 416.40 mi (670.14 km) |
| Old Jamestown to Sudley (Virginia) | 687.94 mi (1,107.14 km) |
| Old Jamestown to Suffern (New York) | 867.69 mi (1,396.42 km) |
| Old Jamestown to Suffolk (Virginia) | 759.08 mi (1,221.61 km) |
