| Old Jamestown to Seymour (Tennessee) | 412.14 mi (663.27 km) |
| Old Jamestown to Shady Hills (Florida) | 846.57 mi (1,362.42 km) |
| Old Jamestown to Shafter (California) | 1,602.30 mi (2,578.65 km) |
| Old Jamestown to Shaker Heights (Ohio) | 495.61 mi (797.61 km) |
| Old Jamestown to Shakopee (Minnesota) | 441.71 mi (710.87 km) |
| Old Jamestown to Sharon (Pennsylvania) | 543.06 mi (873.97 km) |
| Old Jamestown to Sharonville (Ohio) | 316.75 mi (509.77 km) |
| Old Jamestown to Shasta Lake (California) | 1,699.86 mi (2,735.66 km) |
| Old Jamestown to Shawnee (Kansas) | 243.39 mi (391.70 km) |
| Old Jamestown to Shawnee (Oklahoma) | 439.75 mi (707.71 km) |
| Old Jamestown to Sheboygan (Wisconsin) | 363.59 mi (585.13 km) |
| Old Jamestown to Shelby (North Carolina) | 540.31 mi (869.55 km) |
| Old Jamestown to Shelbyville (Indiana) | 245.99 mi (395.89 km) |
| Old Jamestown to Shelbyville (Kentucky) | 276.71 mi (445.33 km) |
| Old Jamestown to Shelbyville (Tennessee) | 312.69 mi (503.22 km) |
