| Old Jamestown to Scottsboro (Alabama) | 372.77 mi (599.91 km) |
| Old Jamestown to Scottsdale (Arizona) | 1,250.42 mi (2,012.36 km) |
| Old Jamestown to Scranton (Pennsylvania) | 791.44 mi (1,273.71 km) |
| Old Jamestown to Seabrook (Maryland) | 721.70 mi (1,161.47 km) |
| Old Jamestown to Seabrook (Texas) | 694.73 mi (1,118.07 km) |
| Old Jamestown to Seaford (New York) | 899.49 mi (1,447.59 km) |
| Old Jamestown to Seagoville (Texas) | 552.83 mi (889.70 km) |
| Old Jamestown to Seal Beach (California) | 1,580.17 mi (2,543.04 km) |
| Old Jamestown to Searcy (Arkansas) | 261.11 mi (420.22 km) |
| Old Jamestown to Seaside (California) | 1,721.49 mi (2,770.47 km) |
| Old Jamestown to SeaTac (Washington) | 1,705.45 mi (2,744.65 km) |
| Old Jamestown to Seattle (Washington) | 1,708.50 mi (2,749.56 km) |
| Old Jamestown to Sebastian (Florida) | 949.49 mi (1,528.05 km) |
| Old Jamestown to Sebring (Florida) | 935.51 mi (1,505.56 km) |
| Old Jamestown to Secaucus (New Jersey) | 869.91 mi (1,399.99 km) |
