| Old Jamestown to Elyria (Ohio) | 466.14 mi (750.18 km) |
| Old Jamestown to Emeryville (California) | 1,727.15 mi (2,779.58 km) |
| Old Jamestown to Emmaus (Pennsylvania) | 793.93 mi (1,277.71 km) |
| Old Jamestown to Emporia (Kansas) | 320.32 mi (515.50 km) |
| Old Jamestown to Encinitas (California) | 1,554.79 mi (2,502.20 km) |
| Old Jamestown to Endicott (New York) | 779.58 mi (1,254.62 km) |
| Old Jamestown to Endwell (New York) | 781.98 mi (1,258.48 km) |
| Old Jamestown to Englewood (Colorado) | 788.20 mi (1,268.49 km) |
| Old Jamestown to Englewood (Florida) | 939.30 mi (1,511.66 km) |
| Old Jamestown to Englewood (New Jersey) | 875.23 mi (1,408.55 km) |
| Old Jamestown to Englewood (Ohio) | 327.06 mi (526.35 km) |
| Old Jamestown to Enid (Oklahoma) | 447.67 mi (720.46 km) |
| Old Jamestown to Ennis (Texas) | 574.02 mi (923.79 km) |
| Old Jamestown to Ensley (Florida) | 599.24 mi (964.39 km) |
| Old Jamestown to Enterprise (Alabama) | 576.30 mi (927.47 km) |
