| Oak Ridge to Southern Pines (North Carolina) | 279.87 mi (450.41 km) |
| Oak Ridge to Southfield (Michigan) | 453.35 mi (729.60 km) |
| Oak Ridge to Southgate (Michigan) | 435.12 mi (700.25 km) |
| Oak Ridge to Southlake (Texas) | 760.70 mi (1,224.23 km) |
| Oak Ridge to Spanaway (Washington) | 2,091.87 mi (3,366.54 km) |
| Oak Ridge to Spanish Fork (Utah) | 1,509.25 mi (2,428.91 km) |
| Oak Ridge to Spanish Lake (Missouri) | 378.72 mi (609.49 km) |
| Oak Ridge to Spanish Springs (Nevada) | 1,935.20 mi (3,114.41 km) |
| Oak Ridge to Sparks (Nevada) | 1,938.07 mi (3,119.02 km) |
| Oak Ridge to Spartanburg (South Carolina) | 150.78 mi (242.66 km) |
| Oak Ridge to Spearfish (South Dakota) | 1,182.01 mi (1,902.26 km) |
| Oak Ridge to Speedway (Indiana) | 285.25 mi (459.06 km) |
| Oak Ridge to Spencer (Iowa) | 761.07 mi (1,224.83 km) |
| Oak Ridge to Spokane (Washington) | 1,869.47 mi (3,008.62 km) |
| Oak Ridge to Spokane Valley (Washington) | 1,860.42 mi (2,994.06 km) |
