| Northampton to Southern Pines (North Carolina) | 3,887.88 mi (6,256.94 km) |
| Northampton to Southfield (Michigan) | 3,701.49 mi (5,956.97 km) |
| Northampton to Southgate (Michigan) | 3,711.72 mi (5,973.44 km) |
| Northampton to Southlake (Texas) | 4,700.97 mi (7,565.49 km) |
| Northampton to Spanaway (Washington) | 4,756.26 mi (7,654.46 km) |
| Northampton to Spanish Fork (Utah) | 4,830.99 mi (7,774.72 km) |
| Northampton to Spanish Lake (Missouri) | 4,141.44 mi (6,665.00 km) |
| Northampton to Spanish Springs (Nevada) | 5,105.30 mi (8,216.19 km) |
| Northampton to Sparks (Nevada) | 5,111.46 mi (8,226.10 km) |
| Northampton to Spartanburg (South Carolina) | 4,002.18 mi (6,440.89 km) |
| Northampton to Spearfish (South Dakota) | 4,342.79 mi (6,989.04 km) |
| Northampton to Speedway (Indiana) | 3,941.13 mi (6,342.63 km) |
| Northampton to Spencer (Iowa) | 4,111.72 mi (6,617.17 km) |
| Northampton to Spokane (Washington) | 4,589.04 mi (7,385.34 km) |
| Northampton to Spokane Valley (Washington) | 4,583.76 mi (7,376.85 km) |
