| Northampton to Scottsboro (Alabama) | 4,182.42 mi (6,730.96 km) |
| Northampton to Scottsdale (Arizona) | 5,193.35 mi (8,357.90 km) |
| Northampton to Scranton (Pennsylvania) | 3,451.12 mi (5,554.04 km) |
| Northampton to Seabrook (Maryland) | 3,607.26 mi (5,805.32 km) |
| Northampton to Seabrook (Texas) | 4,795.29 mi (7,717.27 km) |
| Northampton to Seaford (New York) | 3,395.98 mi (5,465.30 km) |
| Northampton to Seagoville (Texas) | 4,693.60 mi (7,553.62 km) |
| Northampton to Seal Beach (California) | 5,394.50 mi (8,681.62 km) |
| Northampton to Searcy (Arkansas) | 4,375.97 mi (7,042.45 km) |
| Northampton to Seaside (California) | 5,344.68 mi (8,601.44 km) |
| Northampton to SeaTac (Washington) | 4,733.16 mi (7,617.29 km) |
| Northampton to Seattle (Washington) | 4,723.74 mi (7,602.12 km) |
| Northampton to Sebastian (Florida) | 4,297.62 mi (6,916.35 km) |
| Northampton to Sebring (Florida) | 4,353.48 mi (7,006.26 km) |
| Northampton to Secaucus (New Jersey) | 3,414.21 mi (5,494.64 km) |
