| Northampton to Enumclaw (Washington) | 4,738.88 mi (7,626.49 km) |
| Northampton to Ephrata (Pennsylvania) | 3,526.07 mi (5,674.66 km) |
| Northampton to Erie (Colorado) | 4,615.45 mi (7,427.85 km) |
| Northampton to Erie (Pennsylvania) | 3,594.05 mi (5,784.07 km) |
| Northampton to Erlanger (Kentucky) | 3,913.59 mi (6,298.31 km) |
| Northampton to Escanaba (Michigan) | 3,697.81 mi (5,951.06 km) |
| Northampton to Escondido (California) | 5,397.77 mi (8,686.86 km) |
| Northampton to Española (New Mexico) | 4,866.15 mi (7,831.30 km) |
| Northampton to Essex (Maryland) | 3,576.27 mi (5,755.45 km) |
| Northampton to Essex Junction (Vermont) | 3,218.16 mi (5,179.13 km) |
| Northampton to Estelle (Louisiana) | 4,586.18 mi (7,380.74 km) |
| Northampton to Estero (Florida) | 4,421.18 mi (7,115.20 km) |
| Northampton to Euclid (Ohio) | 3,674.20 mi (5,913.05 km) |
| Northampton to Eufaula (Alabama) | 4,282.00 mi (6,891.21 km) |
| Northampton to Eugene (Oregon) | 4,949.94 mi (7,966.15 km) |
