| North Fort Myers to Orangevale (California) | 2,412.09 mi (3,881.88 km) |
| North Fort Myers to Orchards (Washington) | 2,580.67 mi (4,153.19 km) |
| North Fort Myers to Orcutt (California) | 2,342.23 mi (3,769.45 km) |
| North Fort Myers to Oregon (Ohio) | 1,035.33 mi (1,666.21 km) |
| North Fort Myers to Oregon (Wisconsin) | 1,197.01 mi (1,926.40 km) |
| North Fort Myers to Oregon City (Oregon) | 2,576.90 mi (4,147.13 km) |
| North Fort Myers to Orem (Utah) | 1,945.21 mi (3,130.52 km) |
| North Fort Myers to Orinda (California) | 2,456.69 mi (3,953.66 km) |
| North Fort Myers to Orland Park (Illinois) | 1,083.52 mi (1,743.75 km) |
| North Fort Myers to Orlando (Florida) | 125.10 mi (201.32 km) |
| North Fort Myers to Ormond Beach (Florida) | 183.60 mi (295.47 km) |
| North Fort Myers to Oro Valley (Arizona) | 1,788.13 mi (2,877.72 km) |
| North Fort Myers to Oroville (California) | 2,438.57 mi (3,924.50 km) |
| North Fort Myers to Oshkosh (Wisconsin) | 1,252.50 mi (2,015.70 km) |
| North Fort Myers to Oskaloosa (Iowa) | 1,178.95 mi (1,897.34 km) |
