| North Charleston to Superior (Colorado) | 1,470.93 mi (2,367.23 km) |
| North Charleston to Superior (Wisconsin) | 1,143.35 mi (1,840.04 km) |
| North Charleston to Surprise (Arizona) | 1,863.07 mi (2,998.31 km) |
| North Charleston to Susanville (California) | 2,285.11 mi (3,677.53 km) |
| North Charleston to Sussex (Wisconsin) | 833.42 mi (1,341.27 km) |
| North Charleston to Suwanee (Georgia) | 243.48 mi (391.84 km) |
| North Charleston to Swansea (Illinois) | 678.50 mi (1,091.93 km) |
| North Charleston to Sweetwater (Florida) | 492.85 mi (793.17 km) |
| North Charleston to Sweetwater (Texas) | 1,181.16 mi (1,900.90 km) |
| North Charleston to Sycamore (Illinois) | 784.83 mi (1,263.06 km) |
| North Charleston to Sylacauga (Alabama) | 358.86 mi (577.52 km) |
| North Charleston to Sylvania (Ohio) | 640.07 mi (1,030.10 km) |
| North Charleston to Syosset (New York) | 655.68 mi (1,055.22 km) |
| North Charleston to Syracuse (New York) | 731.92 mi (1,177.91 km) |
| North Charleston to Syracuse (Utah) | 1,842.00 mi (2,964.42 km) |
