| North Charleston to Storm Lake (Iowa) | 1,062.38 mi (1,709.74 km) |
| North Charleston to Storrs (Connecticut) | 749.42 mi (1,206.08 km) |
| North Charleston to Stoughton (Wisconsin) | 851.94 mi (1,371.06 km) |
| North Charleston to Stow (Ohio) | 576.28 mi (927.44 km) |
| North Charleston to Streamwood (Illinois) | 770.00 mi (1,239.19 km) |
| North Charleston to Streator (Illinois) | 744.69 mi (1,198.47 km) |
| North Charleston to Streetsboro (Ohio) | 579.99 mi (933.41 km) |
| North Charleston to Strongsville (Ohio) | 588.80 mi (947.58 km) |
| North Charleston to Stuart (Florida) | 394.71 mi (635.23 km) |
| North Charleston to Stuarts Draft (Virginia) | 357.99 mi (576.13 km) |
| North Charleston to Sturgis (Michigan) | 680.60 mi (1,095.32 km) |
| North Charleston to Suamico (Wisconsin) | 916.64 mi (1,475.18 km) |
| North Charleston to Sudley (Virginia) | 431.14 mi (693.86 km) |
| North Charleston to Suffern (New York) | 654.27 mi (1,052.94 km) |
| North Charleston to Suffolk (Virginia) | 326.20 mi (524.97 km) |
