| North Charleston to Smyrna (Delaware) | 506.61 mi (815.32 km) |
| North Charleston to Smyrna (Georgia) | 264.78 mi (426.11 km) |
| North Charleston to Smyrna (Tennessee) | 424.15 mi (682.60 km) |
| North Charleston to Snellville (Georgia) | 236.11 mi (379.98 km) |
| North Charleston to Snoqualmie (Washington) | 2,387.89 mi (3,842.93 km) |
| North Charleston to Snyder (Texas) | 1,208.26 mi (1,944.51 km) |
| North Charleston to Socastee (South Carolina) | 81.73 mi (131.53 km) |
| North Charleston to Socorro (Texas) | 1,528.48 mi (2,459.85 km) |
| North Charleston to Soddy-Daisy (Tennessee) | 334.01 mi (537.53 km) |
| North Charleston to Solana Beach (California) | 2,144.45 mi (3,451.16 km) |
| North Charleston to Soledad (California) | 2,339.97 mi (3,765.82 km) |
| North Charleston to Solon (Ohio) | 590.70 mi (950.63 km) |
| North Charleston to Somers Point (New Jersey) | 537.54 mi (865.08 km) |
| North Charleston to Somerset (Kentucky) | 386.25 mi (621.62 km) |
| North Charleston to Somerset (New Jersey) | 608.84 mi (979.84 km) |
