| North Charleston to Silver Firs (Washington) | 2,405.93 mi (3,871.98 km) |
| North Charleston to Silver Spring (Maryland) | 454.38 mi (731.26 km) |
| North Charleston to Silver Springs Shores (Florida) | 286.26 mi (460.69 km) |
| North Charleston to Silverdale (Washington) | 2,428.11 mi (3,907.67 km) |
| North Charleston to Silverton (Oregon) | 2,409.81 mi (3,878.22 km) |
| North Charleston to Simi Valley (California) | 2,214.71 mi (3,564.23 km) |
| North Charleston to Simpsonville (South Carolina) | 177.68 mi (285.96 km) |
| North Charleston to Sioux City (Iowa) | 1,107.93 mi (1,783.05 km) |
| North Charleston to Sioux Falls (South Dakota) | 1,161.23 mi (1,868.81 km) |
| North Charleston to Skokie (Illinois) | 757.33 mi (1,218.80 km) |
| North Charleston to Sleepy Hollow (New York) | 660.63 mi (1,063.19 km) |
| North Charleston to Slidell (Louisiana) | 599.13 mi (964.21 km) |
| North Charleston to Smithfield (North Carolina) | 205.23 mi (330.29 km) |
| North Charleston to Smithfield (Utah) | 1,837.03 mi (2,956.42 km) |
| North Charleston to Smithville (Missouri) | 923.26 mi (1,485.84 km) |
