| North Charleston to Seymour (Tennessee) | 294.11 mi (473.33 km) |
| North Charleston to Shady Hills (Florida) | 344.08 mi (553.74 km) |
| North Charleston to Shafter (California) | 2,228.74 mi (3,586.82 km) |
| North Charleston to Shaker Heights (Ohio) | 597.50 mi (961.59 km) |
| North Charleston to Shakopee (Minnesota) | 1,089.21 mi (1,752.91 km) |
| North Charleston to Sharon (Pennsylvania) | 575.84 mi (926.73 km) |
| North Charleston to Sharonville (Ohio) | 502.46 mi (808.64 km) |
| North Charleston to Shasta Lake (California) | 2,377.62 mi (3,826.41 km) |
| North Charleston to Shawnee (Kansas) | 924.29 mi (1,487.50 km) |
| North Charleston to Shawnee (Oklahoma) | 979.55 mi (1,576.43 km) |
| North Charleston to Sheboygan (Wisconsin) | 855.04 mi (1,376.05 km) |
| North Charleston to Shelby (North Carolina) | 185.00 mi (297.73 km) |
| North Charleston to Shelbyville (Indiana) | 557.34 mi (896.95 km) |
| North Charleston to Shelbyville (Kentucky) | 466.86 mi (751.33 km) |
| North Charleston to Shelbyville (Tennessee) | 406.04 mi (653.47 km) |
