| North Charleston to Santa Rosa (California) | 2,401.76 mi (3,865.26 km) |
| North Charleston to Santaquin (Utah) | 1,818.91 mi (2,927.25 km) |
| North Charleston to Santee (California) | 2,130.63 mi (3,428.92 km) |
| North Charleston to Sapulpa (Oklahoma) | 936.75 mi (1,507.56 km) |
| North Charleston to Saraland (Alabama) | 491.89 mi (791.62 km) |
| North Charleston to Sarasota (Florida) | 412.04 mi (663.11 km) |
| North Charleston to Sarasota Springs (Florida) | 412.54 mi (663.92 km) |
| North Charleston to Saratoga (California) | 2,371.64 mi (3,816.79 km) |
| North Charleston to Saratoga Springs (New York) | 780.66 mi (1,256.36 km) |
| North Charleston to Saratoga Springs (Utah) | 1,827.90 mi (2,941.72 km) |
| North Charleston to Sartell (Minnesota) | 1,155.88 mi (1,860.21 km) |
| North Charleston to Satellite Beach (Florida) | 328.22 mi (528.22 km) |
| North Charleston to Sauk Rapids (Minnesota) | 1,152.58 mi (1,854.89 km) |
| North Charleston to Sault Ste. Marie (Michigan) | 965.01 mi (1,553.03 km) |
| North Charleston to Savage (Minnesota) | 1,084.24 mi (1,744.92 km) |
