| North Charleston to Des Plaines (Illinois) | 762.14 mi (1,226.54 km) |
| North Charleston to Desert Hot Springs (California) | 2,093.09 mi (3,368.50 km) |
| North Charleston to DeSoto (Texas) | 974.90 mi (1,568.95 km) |
| North Charleston to Destin (Florida) | 414.28 mi (666.72 km) |
| North Charleston to Destrehan (Louisiana) | 639.78 mi (1,029.62 km) |
| North Charleston to Detroit (Michigan) | 675.31 mi (1,086.80 km) |
| North Charleston to Diamond Bar (California) | 2,164.77 mi (3,483.85 km) |
| North Charleston to Diamond Springs (California) | 2,300.03 mi (3,701.54 km) |
| North Charleston to Dickinson (North Dakota) | 1,534.22 mi (2,469.08 km) |
| North Charleston to Dickinson (Texas) | 916.51 mi (1,474.98 km) |
| North Charleston to Dickson (Tennessee) | 469.02 mi (754.81 km) |
| North Charleston to Difficult Run (Virginia) | 441.33 mi (710.25 km) |
| North Charleston to Dinuba (California) | 2,231.84 mi (3,591.80 km) |
| North Charleston to Discovery Bay (California) | 2,344.53 mi (3,773.16 km) |
| North Charleston to Dix Hills (New York) | 660.05 mi (1,062.25 km) |
