| Nipomo to Southern Pines (North Carolina) | 2,305.68 mi (3,710.64 km) |
| Nipomo to Southfield (Michigan) | 2,053.55 mi (3,304.88 km) |
| Nipomo to Southgate (Michigan) | 2,055.80 mi (3,308.49 km) |
| Nipomo to Southlake (Texas) | 1,342.11 mi (2,159.92 km) |
| Nipomo to Spanaway (Washington) | 839.62 mi (1,351.23 km) |
| Nipomo to Spanish Fork (Utah) | 598.18 mi (962.68 km) |
| Nipomo to Spanish Lake (Missouri) | 1,685.57 mi (2,712.67 km) |
| Nipomo to Spanish Springs (Nevada) | 322.77 mi (519.45 km) |
| Nipomo to Sparks (Nevada) | 316.73 mi (509.73 km) |
| Nipomo to Spartanburg (South Carolina) | 2,169.55 mi (3,491.55 km) |
| Nipomo to Spearfish (South Dakota) | 1,097.50 mi (1,766.25 km) |
| Nipomo to Speedway (Indiana) | 1,896.35 mi (3,051.87 km) |
| Nipomo to Spencer (Iowa) | 1,463.04 mi (2,354.53 km) |
| Nipomo to Spokane (Washington) | 887.18 mi (1,427.77 km) |
| Nipomo to Spokane Valley (Washington) | 888.75 mi (1,430.30 km) |
