| Nicosia to Sangeorz-Bai | 954.44 mi (1,536.02 km) |
| Nicosia to Sannicolau Mare | 1,004.23 mi (1,616.15 km) |
| Nicosia to Santana | 988.66 mi (1,591.10 km) |
| Nicosia to Satu Mare | 1,024.53 mi (1,648.82 km) |
| Nicosia to Scobinti | 906.58 mi (1,459.00 km) |
| Nicosia to Scornicesti | 799.00 mi (1,285.87 km) |
| Nicosia to Sebes | 903.92 mi (1,454.72 km) |
| Nicosia to Seini | 1,011.61 mi (1,628.04 km) |
| Nicosia to Sfantu-Gheorghe | 838.15 mi (1,348.87 km) |
| Nicosia to Sibiu | 877.79 mi (1,412.67 km) |
| Nicosia to Sighetu Marmatiei | 1,006.54 mi (1,619.87 km) |
| Nicosia to Sighisoara | 884.24 mi (1,423.04 km) |
| Nicosia to Simeria | 914.91 mi (1,472.41 km) |
| Nicosia to Sinaia | 814.06 mi (1,310.10 km) |
| Nicosia to Slatina | 797.28 mi (1,283.10 km) |
