| Nicosia to Spilamberto | 1,344.04 mi (2,163.03 km) |
| Nicosia to Spilimbergo | 1,307.30 mi (2,103.89 km) |
| Nicosia to Spinea | 1,318.75 mi (2,122.33 km) |
| Nicosia to Spoleto | 1,223.98 mi (1,969.80 km) |
| Nicosia to Spoltore | 1,147.27 mi (1,846.35 km) |
| Nicosia to Spresiano | 1,323.57 mi (2,130.08 km) |
| Nicosia to Squinzano | 910.06 mi (1,464.60 km) |
| Nicosia to Statte | 955.36 mi (1,537.50 km) |
| Nicosia to Stezzano | 1,434.25 mi (2,308.21 km) |
| Nicosia to Strada | 1,307.62 mi (2,104.40 km) |
| Nicosia to Stradella | 1,436.18 mi (2,311.31 km) |
| Nicosia to Striano | 1,092.61 mi (1,758.39 km) |
| Nicosia to Subiaco | 1,186.70 mi (1,909.81 km) |
| Nicosia to Sulmona | 1,148.54 mi (1,848.39 km) |
| Nicosia to Surbo | 905.17 mi (1,456.73 km) |
